Cell Lines and Cell Cultures
Thermo Scientific™ GeneBLAzer™ M1-NFAT-bla CHO-K1 Cells
GeneBLAzer™ M1-NFAT-bla CHO-K1 cells contain the human Acetylcholine (muscarinic) subtype 1 receptor (M1) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ ADRA2A-bla U2OS Cells
The Tango™ ADRA2A-bla U2OS cells contain the human Adrenergic, Alpha-2A-, Receptor (ADRA2A) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ TRα-UAS-bla HEK 293T Assay Kit
TR alpha-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human Thyroid hormone receptor alpha(TR alpha) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
Thermo Scientific™ Tango™ CXCR6-bla U2OS Cells
The Tango™ CXCR6-bla U2OS cells contain the human Chemokine (C-X-C motif) receptor 6 (CXCR6) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ LanthaScreen™ ERK2 U2OS Cell Line
The Map Kinase (MapK) signal transduction cascade is activated by growth factors such as EGF, PDGF, and HGF. Binding of these factors to their respective cell surface receptors results in the initiation of receptor tyrosine kinase activity.
Thermo Scientific™ GeneBLAzer™ CCKAR-NFAT-bla HEK 293T Cells
The GeneBLAzer™ CCKAR-NFAT-bla CHO-K1 cells contain the human Cholecystokinin A Receptor (CCKAR) stably integrated into the GeneBLAzer™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ SSTR1-bla U2OS Cells
The Tango™ SSTR1-bla U2OS cells contain the human Somatostatin Receptor 1 (SSTR1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ OPRL1-Gqi5-NFAT-bla FreeStyle™ 293F Cells
The GeneBLAzer™ OPRL1-Gqi5-NFAT-bla FreeStyle™ 293F Cell Line contains the human opioid/opiate receptor-like-1 receptor (OPRL1) stably integrated into the GeneBLAzer™ Gqi5-NFAT-bla FreeStyle™ 293F Cell Line.
Thermo Scientific™ GeneBLAzer™ MC4R-CRE-bla CHO-K1 Cells
GeneBLAzer™ MC4R-CRE-bla CHO-K1 cells contain the human Melanocortin Receptor 4 (MC4R) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ LanthaScreen™ STAT1 U2OS Cell Line
The JAK/STAT1 signaling pathway is known to be activated by type I/II interferons such as interferon-gamma and interferon-alpha.
Thermo Scientific™ LanthaScreen™ ATF2 (19-106) A549 Cell Line
Contains a fusion protein consisting of GFP and a fragment encoding for aa 19-106 of ATF2 under the control of a CMV promotor
Thermo Scientific™ CellSensor™ ESRE-bla HeLa Cell Line
Endoplasmic Reticulum (ER) stress is associated with a variety of pathophysiological conditions, such as neurodegenerative diseases, diabetes, tumor growth under hypoxic conditions, and ischemic heart disease.
Thermo Scientific™ CellSensor™ Gli-bla 22Rv.1 Cell Line
The morphogenic signal Shh provides in the developing CNS induces proliferation of neuronal precursor cells in the developing cerebellum and other tissues.
Thermo Scientific™ GeneBLAzer™ HTR2C-NFAT-bla CHO-K1 Cells
GeneBLAzer™ HTR2C-NFAT-bla CHO-K1 cells contain the human 5-hydroxytrptamine (serotonin) receptor 2C (HTR2C), (Accession No. NM_000868.1) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ MCHR2-bla U2OS Cells
The Tango™ MCHR2-bla U2OS cells contain the human Melanin-concentrating hormone receptor 2 (MCHR2) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.