Cell Lines and Cell Cultures
Thermo Scientific™ GeneBLAzer™ OPRK1-Gqo5-NFAT-bla CHO-K1 Cells
The GeneBLAzer™ OPRK-1-Gqo5-NFAT-bla CHO-K1 cells contain the human Opioid Receptor Kappa 1 (OPRK1) (Accession No. NM_000710) stably integrated into the GeneBLAzer™ Gqo5-NFAT-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ GPR8-bla U2OS Cells
The Tango™ GPR8-bla U2OS cells contain the human Neuropeptides B/W receptor 2 (GPR8) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ D1-CRE-bla CHO-K1 Cells
GeneBLAzer™ D1-CRE-bla CHO-K1 cells contain the human Dopamine Receptor 1 (D1) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ TRβ-UAS-bla HEK 293T Cells
TR beta-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human Thyroid hormone receptor beta(TR beta) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UASbla HEK 293T cell line.
Thermo Scientific™ LanthaScreen™ c-Jun (1-79) HeLa Cell Line
The LanthaScreen™ c-Jun (1-79) HeLa cell line contains a fusion protein consisting of GFP and a fragment encoding for AA 1-79 of c-Jun under the control of a CMV promoter stably transfected into HeLa cell lines.
Thermo Scientific™ CellSensor™ NFkB-bla RAW 264.7 Cell Line
The CellSensor™ NFκB-bla RAW264.7 mouse macrophage cell line contains a beta-lactamase reporter gene under control of a stably integrated NFκB response element.
Thermo Scientific™ GeneBLAzer™ RARα-UAS-bla HEK 293T Cells
RAR alpha-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human retinoic acid receptor alpha fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK293T cell line.
Thermo Scientific™ GeneBLAzer™ LXRβ-UAS-bla HEK 293T Cells
LXR beta-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human Liver-X receptor-beta (LXR beta) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
Thermo Scientific™ GeneBLAzer™ TRα-UAS-bla HEK 293T Assay Kit
TR alpha-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human Thyroid hormone receptor alpha(TR alpha) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
Thermo Scientific™ CellSensor™ LEF/TCF-bla HCT-116 Cell Line
Wnt signaling via Beta-catenin plays a central role in development and homeostasis. This pathway is invariably disrupted in colorectal tumors and commonly affected by mutation in other cancers.
Thermo Scientific™ GeneBLAzer™ RARβ-UAS-bla HEK 293T Cells
RAR beta-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human retinoic acid receptor beta (RAR beta) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
Thermo Scientific™ GeneBLAzer™ RXRβ-UAS-bla HEK 293T Cells
RXR beta-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human Retinoid X Receptor beta (RXR beta) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
Thermo Scientific™ LanthaScreen™ ERK2 U2OS Cell Line
The Map Kinase (MapK) signal transduction cascade is activated by growth factors such as EGF, PDGF, and HGF. Binding of these factors to their respective cell surface receptors results in the initiation of receptor tyrosine kinase activity.
Thermo Scientific™ CellSensor™ ISRE-bla HEK293T Cell Line
The CellSensor™ ISRE-bla HEK 293T cell line is responsive to interferon alpha and can be used to probe the JAK/STAT signaling pathway.
Thermo Scientific™ CellSensor™ NFκB-bla RA 1 Cell Line
The CellSensor™ NFκB-bla RA-1 cell line contains a beta-lactamase reporter gene under control of the NFκB response element stably integrated into Ramos 1 (RA-1) cells.